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            Native MS-Guided Structural Biology

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            –Vicki Wysocki, Director

             

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            The Resource for Native Mass Spectrometry Guided Structural Biology (nMS→SB) was established in 2018 with a 6.8M P41 grant from the NIH National Institute of General Medical Sciences. As a national 超简单易用 超级兔子虚拟磁盘加速器点评-太平洋电脑网:2021年8月7日 - 超级兔子虚拟磁盘加速器现在改名为超级兔子加速器(也叫超级兔子加速盘等其他名字),超级兔子虚拟磁盘加速器是一款将内存当虚拟硬盘使用的Ramdisk工具,..., our purpose is to develop and disseminate novel technologies throughout the broader biomedical research community. Our mission is to develop improved native MS as a routine tool and disseminate the technology to the biomedical research community through vendor partnerships and training. The Resource will work with investigators across the nation and globe on challenging biomedical projects ranging from viral hemorrhagic fevers and HIV to cataract formation and neurological disorders.

             

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            We are building an integrated MS-based workflow for intact, native complexes, with state-of-the-art instrumentation and software that can answer the desired structural biology questions.

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            Collaboration is key to advancing technologies and their applications for structural biology.

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            A leadership team coordinates all activities of the Resource, under the direction of Vicki Wysocki, with Resource personnel consisting of PhD scientists, postdoctoral researchers, and graduate students from The Ohio State University, Texas A&M, and West Virginia University.

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            Advanced instrumentation, software tools, and protocols allow biomedical investigators to make progress on structural biology problems with lower sample amounts, more rapidly, and with more rigor than currently possible.

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            Publications include advances in our technology research and development projects, as well as research with our collaborators in Driving Biomedical Projects (DBPs) and Collaboration and Service (C&S) projects.

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